出生 住院 心脏和呼吸道并发症 在SARS-CoV-2德尔塔变异期间 主导地位
Ruiyan M Wang1, Alexander Friedman1, Whitney A Booker1
1Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, New York.
American journal of perinatology
|September 2, 2024
概括
COVID-19的三角洲变种增加了产妇在分娩期间住院期间心脏和呼吸道并发症的风险. 这种菌株与孕妇的临床负担更高有关.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 德尔塔变种在2021年成为主要的.
- 以前的研究表明,与三角洲变种相关的孕产妇风险可能会增加,但证据尚未确定.
研究的目的:
- 调查SARS-CoV-2 Delta变种与国家分娩住院病例样本中心脏和呼吸道并发症风险之间的关联.
主要方法:
- 分析2021年全国分娩住院数据,比较Delta前 (一月至六月) 和Delta期间 (七月至十二月) 的队列.
- 检查了2019年冠状病毒病 (COVID-19) 诊断和相关的心脏和呼吸道并发症的发生率.
主要成果:
- 德尔塔期与呼吸道并发症 (aOR=1.54) 和心脏严重孕产妇发病率 (SMM) (aOR=1.54) 的调整后几率增加有关.
- 在被诊断为COVID-19的分娩中,三角洲时期的呼吸道并发症 (8.4%与3.7%) 和心脏SMM (8.4%与3.5%) 的发病率高于三角洲前时期.
- 德尔塔变种与增加的孕产妇人口水平临床负担有关.
结论:
- SARS-CoV-2的三角洲变种与孕妇心脏和呼吸道并发症风险显著增加有关.
- 研究结果支持,三角洲菌株导致了对孕产妇人口的更大的临床负担.
- "三角洲"疫情期间,在被诊断为COVID-19的分娩中,出现不良结果的风险增加.
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