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Updated: Jun 14, 2025

Co-localization of Cell Lineage Markers and the Tomato Signal
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通过CRISPR激活系统激活UCHL1,促进了由HIF-1α/SOX9介导的软骨分化

Shanwei Shi1,2, Yang Ge1,2, Qiqian Yan1,2

  • 1School of Stomatology, Stomatological Hospital, Southern Medical University, Guangzhou, China.

Journal of cellular and molecular medicine
|September 3, 2024
PubMed
概括

激活Ubiquitin C-终端酶L1 (UCHL1) 通过增强缺氧诱导因子-1α (HIF-1α) 稳定性和干细胞中的SOX9表达,促进软骨再生. 这种CRISPR激活策略显示出对软骨组织工程的前景.

关键词:
克里斯普尔是什么意思?克里斯普尔是什么意思?混凝土的生成 混凝土的生成缺氧诱导因子-1α.乌比奎丁C-终端酸酶L1的使用

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