冷血在口腔伤口愈合过程中的有效性:一个范围审查
Reyhaneh Shoorgashti1, Reza Nikmaram2, Yasaman Azimi3
1Department of Oral and Maxillofacial Medicine, School of Dentistry, Islamic Azad University of Medical Sciences, Tehran, Iran.
Oral diseases
|September 3, 2024
概括
冷大气等离子体 (CAP) 通过影响细胞活力,基因表达和炎症,促进口腔伤口愈合. 这份对13项研究的综述证实了CAP的研究结果.
科学领域:
- 生物医学工程 生物医学工程
- 等离子体物理学的物理学
- 再生医学是一种再生医学.
背景情况:
- 冷大气等离子体 (CAP) 为伤口愈合提供了一种非热疗法.
- CAP的生物效应源于其反应性物种,这些物种可以调节细胞过程.
研究的目的:
- 评估冷大气等离子体 (CAP) 在加速口腔伤口愈合方面的疗效.
- 综合来自细胞,动物和人类研究的证据,研究CAP在口腔组织修复中的作用.
主要方法:
- 电子数据库 (PubMed/Medline,Embase,科学网,Scopus) 和灰色文献的综合范围审查.
- 纳入标准重点是研究CAP对口腔伤口或细胞的影响,直到2023年10月.
主要成果:
- 对13项研究 (7个细胞,1个动物,5个人类) 的分析表明了CAP的治疗潜力.
- CAP的应用维持了细胞活力,影响了基因表达,加速了愈合,并调节了炎症细胞因子.
- 介电屏障放电 (DBD) 血显示出时间依赖的细胞效应,而微血辐射增强了细胞数量和迁移.
结论:
- 在各种研究模型中,冷大气等离子体 (CAP) 对口腔伤口愈合有显著的积极影响.
- CAP提出了一种有前途的非热疗法来增强口腔组织的再生和修复.
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