食黑色素改变了 brojler cecum 的微生物多样性和新陈代谢
Li Zhen1,2,3, Yi Huang1, Xuewen Bi1
1College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, China.
Frontiers in microbiology
|September 3, 2024
概括
在 brojlers 中补充黑素改变了肠道微生物的多样性,并增加了诸如 Bacteroides 和 Firmicutes 等有益细菌. 这增强了肉的消化和代谢功能,改善了整体健康.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 营养生物化学 营养生物化学
背景情况:
- 肠道微生物群在肉健康中起着至关重要的作用,影响消化,营养吸收和新陈代谢.
- 黑激素是一种具有抗氧化和抗炎性能的激素,在动物营养中具有潜在的应用.
研究的目的:
- 研究食补充黑素对肉肠道微生物组成和功能的影响.
- 评估黑激素对肉消化和代谢能力的影响.
主要方法:
- 160只罗斯308肉被分为四组,接受0,20,40或80毫克/公斤的黑素.
- 使用基于丰度的覆盖率估计器 (ACE) 和测序分析了肠道微生物群落.
- 使用基因和基因组的京都百科全书 (KEGG) 和正统组集群 (COG) 分析来评估功能性基因表达.
主要成果:
- 补充黑素,特别是40毫克/公斤,增加了Bacteroidetes和Ruminococcus spp.的相对丰度. 在 brojiler 肠道中.
- 功能性分析表明,黑激素可以调高参与细胞过程,环境信息处理和新陈代谢的基因.
- M80组显示ACE指数下降,这表明在较高剂量时微生物多样性减少.
结论:
- 饮食中补充黑激素可以调节肉的肠道微生物群组成,有利于有益的细菌.
- 黑色素积极影响肉的消化,吸收和代谢功能.
- 最佳的黑激素剂量至关重要,因为高水平可能会降低微生物多样性.
相关概念视频
Microbial Nutrition
Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
Amino Acid Catabolism
Microorganisms rely on proteins as an essential carbon and energy source, particularly in environments with limited polysaccharides or lipids. However, proteins are too large to cross the plasma membrane unaided, necessitating enzymatic degradation. Microbes secrete extracellular proteases and peptidases that hydrolyze proteins into peptides, which can then be transported across the membrane. Once inside the cell, intracellular proteases degrade these peptides into free amino acids, which...
Development of Human Microbiota
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Microbiota of the Large Intestine
The large intestine hosts the most densely populated microbial ecosystem in the human body. This complex community primarily consists of anaerobic bacteria, with Bacillota (formerly Firmicutes) and Bacteroidota (formerly Bacteroidetes) as the predominant groups. The distribution of these microbes varies along different sections of the large intestine, influenced by local environmental factors such as oxygen availability and nutrient composition.The cecum, located at the beginning of the large...
Dysbiosis of the Gut Microbiota
The human gut microbiome includes a diverse array of microbial species, including beneficial commensals and opportunistic pathogens, which interact to support host health. These microbes contribute to essential functions such as nutrient metabolism, immune system modulation, and maintenance of intestinal barrier integrity. However, disruptions to this equilibrium—referred to as dysbiosis—can have widespread physiological consequences.Dysbiosis is often characterized by reduced microbial...
Microbiota Modulation by Antibiotics
Antibiotics have revolutionized modern medicine by saving countless lives from bacterial infections. However, their widespread use has inadvertently harmed the delicate balance of the human gut microbiota. The gut microbiota, a complex community of bacteria, archaea, viruses, and fungi, plays a vital role in regulating metabolism, immune responses, and maintaining intestinal health. Antibiotics, especially broad-spectrum types, disrupt this ecosystem by eradicating both harmful and beneficial...


