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相关概念视频

Genome Annotation and Assembly03:36

Genome Annotation and Assembly

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The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
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Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

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Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
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Evolutionary Relationships through Genome Comparisons02:54

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Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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RACE - Rapid Amplification of cDNA Ends02:35

RACE - Rapid Amplification of cDNA Ends

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Rapid Amplification of cDNA Ends, or RACE, is one of the most effective methods to obtain a full-length cDNA from an mRNA sequence between a known internal region to the unknown sequence at the 5’ or 3’ end. The unknown region is cloned in the cDNA by a gene-specific primer that binds the known end, and a hybrid primer that attaches a predefined anchor sequence to the unknown end of the cDNA. The sequence in between is amplified by PCR with an anchor primer and a gene-specific...
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Complementary DNA01:44

Complementary DNA

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Overview
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相关实验视频

Updated: Jun 14, 2025

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
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阿斯特拉系基因组数据库:阿斯特拉系基因组学综合平台.

Liang Wang1,2, Hanting Yang3, Guoqing Xu3

  • 1State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.

Frontiers in plant science
|September 3, 2024
PubMed
概括

阿斯特拉属植物基因组数据库 (AGD) 提供了一个集中资源,用于分析各种阿斯特拉属植物基因组. 这个平台有助于研究人员在基因注释,育种和理解这一重要的植物家族的进化生物学.

关键词:
星座科 (Asteraceae) 是一个植物.星座植物基因组数据库 (AGD)分析工具 分析工具基因组 基因组是基因组的组成部分.分类学 分类学.

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Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics
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科学领域:

  • 植物基因组学 植物基因组学
  • 生物信息学是一种生物信息学.
  • 生物多样性保护 生物多样性保护

背景情况:

  • 阿斯特拉科,最大的树苗家族,具有重要的药用和园艺价值.
  • 阿斯特拉属植物物种复杂的遗传背景给基因组研究带来了挑战.
  • 测序技术的进步已经为Asteraceae产生了大量的基因组数据.

研究的目的:

  • 为Asteraceae物种开发一个全面的,集中的基因组资源.
  • 为了促进基因注释,基因家族分析和进化研究.
  • 支持在Asteraceae家族内的遗传育种和生物多样性保护工作.

主要方法:

  • 开发了Asteraceae基因组学数据库 (AGD).
  • 集成高质量的基因组和有机体基因组数据.
  • 包括诸如BLAST,JBrowse和CRISPRCasFinder等分析工具.

主要成果:

  • AGD为Asteraceae基因组研究提供了一个系统的平台.
  • 该数据库可以方便地查询,分析和比较基因组信息.
  • 一套生物信息学工具集成用于各种分析需求.

结论:

  • AGD是推动Asteraceae基因组学的重要资源.
  • 该数据库赋予了基因注释,进化生物学和遗传育种方面的研究人员权力.
  • AGD有助于促进遗传育种和保护生物多样性.