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Updated: Jun 14, 2025

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第1型先天性淋巴细胞:在肉病症中是一种生物标志物和治疗候选物

Inchul Cho1,2, Andrew L Ji1,2,3,4,5

  • 1Department of Dermatology.

The Journal of clinical investigation
|September 3, 2024
PubMed
概括

研究人员发现,1型先天性淋巴细胞 (ILC1s) 在型硬化症患者中积累. 通过阻断CXCL12/CXCR4通路,可以通过减少颗粒瘤形成来治疗沙丘病.

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T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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