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Updated: Jun 14, 2025

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
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药理性LDH抑制重定向内葡萄糖吸收,并改善固体瘤模型中的抗瘤免疫力

Svena Verma1,2,3, Sadna Budhu1,2,3, Inna Serganova3,4

  • 1Pharmacology Program.

The Journal of clinical investigation
|September 3, 2024
PubMed
概括

乳酸脱酶抑制剂 (LDHi) 重新编程瘤微环境,使癌细胞饥饿,同时促进T细胞功能. 这种策略通过改善T细胞透和抗瘤免疫力来提高免疫疗法的有效性.

关键词:
癌症免疫疗法癌症免疫疗法葡萄糖的新陈代谢.免疫学 免疫学 免疫学代谢过程中的代谢.药理学 药理学是指药理学的学科.

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