完全覆盖的自我扩展金属支架用于耐火良性胰腺管道收紧:系统性审查和元分析
Gajanan Rodge1, Suprabhat Giri2, Kailash Kolhe3
1Department of Gastroenterology, Bombay Hospital & Medical Research Centre.
Surgical laparoscopy, endoscopy & percutaneous techniques
|September 3, 2024
概括
完全覆盖的自扩展金属支架 (FCSEMS) 显示胰腺管狭窄的高分辨率. 虽然有效,但 de novo 狭窄形成是一个需要进一步研究最佳治疗算法的问题.
科学领域:
- 胃肠病学 胃肠病学
- 干预性内镜检查是干预性的内镜检查.
- 胆汁干预 胆汁干预
背景情况:
- 耐火性胰腺管狭窄通常需要多个塑料支架.
- 完全覆盖的自扩展金属支架 (FCSEMS) 正成为一种潜在的替代方案.
- 本综述评估了FCSEMS在胰腺管狭窄的疗效和安全性.
研究的目的:
- 系统地审查FCSEMS在治疗胰腺管狭窄的疗效.
- 在此背景下,评估FCSEMS的安全性和不良事件概况.
- 为了确定收缩和相关疼痛的解决率.
主要方法:
- 在MEDLINE,EMBASE和Scopus数据库中进行了系统的文献搜索.
- 包括到2022年11月发表的研究.
- 使用随机效应模型计算了有效性和安全性结果的聚合比例.
主要成果:
- 对22项涉及439名患者的研究的分析显示,结合的狭窄症解决率为91.6%.
- 疼痛缓解率为84.9%,急性胰腺炎发病率低 (3.9%) 和需要切除支架的疼痛 (0.8%).
- 发现了支架迁移 (12.9%),收缩复发 (9.3%) 和新收缩形成 (3.3%) 的不良事件.
结论:
- FCSEMS在解决良性胰腺管狭窄方面表现出高效,安全性可接受.
- 新生狭窄形成是一个重要的并发症,需要注意.
- 需要进一步的研究来确定FCSEMS在治疗算法中的最终作用.
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