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精油对糖尿病的改善作用:一篇综述

Pervej Alom Barbhuiya^1,2, Diamond Pariong^1,2, Asif Pervice Alam^1,2

¹Faculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, PIN - 781026, India.

Current topics in medicinal chemistry

|September 3, 2024

概括

植物精油在治疗糖尿病方面表现有前途. 这些天然疗法可以通过各种机制改善血糖控制,为合成药物提供更安全的替代品.

科学领域:

药理学药理学是指药理学的学科.
自然产品自然产品
代谢障碍代谢障碍代谢障碍

背景情况:

糖尿病 (DM) 是一个重要的全球健康问题,每年造成数百万人的死亡.
传统的DM合成药物,如甲福明,可能会导致不良反应和并发症.
来自植物的精油 (EO) 以其治疗性质而闻名,包括抗微生物和抗炎作用.

研究的目的:

审查具有抗糖尿病活性的精油 (EO) 的临床前和临床证据.
总结EO在糖尿病管理中的拟议作用机制.
为未来的糖尿病药物开发确定潜在的植物衍生EO.

主要方法:

在科学数据库 (谷歌学者,PubMed,科学网) 中进行了全面的文献搜索.
包括调查EO在临床前和临床环境中的抗糖尿病潜力的研究.
关于植物来源,生物活性化合物和作用机制的数据被提取和合成.

主要成果:

临床前研究确定了来自20种不同的植物物种的EO的抗糖尿病潜力.
临床试验表明,尼日利亚 (Nigella sativa) 和 (Cuminum cyminum) 精油在控制血糖水平方面具有有效性.
发现EO中的关键生物活性化合物,如卡瓦克罗尔和蒂摩尔,可以抑制关键酶 (α-GLUC,α-氨酶,脂酶) 和调节信号通路 (GLUT-4,AKT酸化).

结论:

来自各种植物来源的精油具有显著的抗糖尿病特性.
这些天然化合物为开发糖尿病管理的新型治疗策略提供了有希望的途径.
需要进一步的临床研究,以充分阐明EO在糖尿病治疗和药物发现方面的潜力.

关键词:

生物活性植物成分植物成分.这是临床的.糖尿病是一种糖尿病.精油精油精油精油临床前的临床前的传统医学是传统的医学.

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