细菌子的耐药性:对对高性能消毒剂的菌株特异反应的影响
Simone Sommerfeld1, Lidianne Fabricia Dos Santos Tomais2, Lara Reis Gomes2
1Faculty of Veterinary Medicine, Federal University of Uberlândia, Av. Pará, 1720, Campus Umuarama, Bloco 2 E, CEP 38405-320, Uberlândia, Minas Gerais, Brazil. simone.sommerfeld@ufu.br.
Current microbiology
|September 3, 2024
概括
甲甲 (OPA) 和四级氨甲 (AG) 溶液显示出甲作为消毒细菌子的替代品的潜力. 然而,它们的有效性因细菌菌株而异,需要进一步研究以获得广泛的应用.
科学领域:
- 微生物学 微生物学
- 生物安全是生物安全.
- 消毒和杀菌 消毒和杀菌
背景情况:
- 细菌子在材料和设备中存在重大生物安全风险.
- 有效的消毒方法对于控制子污染至关重要.
研究的目的:
- 为了评估Ortho-phthalaldehyde (OPA) 和四级氨-甲溶液 (AG) 的杀菌效果.
- 将OPA和AG与Bacillus thuringiensis (BT),B. cereus (BC) 和两个B. velezensis (BV1,BV2) 菌株进行比较.
- 评估OPA和AG作为消毒中甲的潜在替代品.
主要方法:
- 用OPA (干) 和AG (喷雾) 处理BT,BC,BV1和BV2的子,其度和持续时间各不相同.
- 进行了最小杀菌度 (MBC) 测试.
- 甲被用作一种控制消毒剂.
主要成果:
- 最初的OPA和AG治疗显示出有限的杀菌作用.
- 增加的OPA度和持续时间对BT有效,但对BV1.
- 在所有经过测试的Bacillus菌株中,AG显示出有限的杀菌效应.
- OPA显示了取决于菌株的杀菌活性,对BT和BV1有效,但对BC和BV2无效.
- 甲在很大程度上是有效的,但并没有完全禁用BV2子.
结论:
- OPA和AG显示出作为湿消毒的甲替代品的潜力.
- OPA和AG的杀菌效果取决于菌株.
- 需要进一步的研究来优化OPA和AG,以实现全面的细菌子无活化.
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