药剂师干预对不适当继续服用抗精神病药物在ICU出院后的影响
Lauren T Dickman1, Kelsey Bauman1, Christopher K Carter1
1Department of Pharmacy, SSM Health St Louis, Fenton, MO, USA.
Journal of pharmacy practice
|September 3, 2024
概括
药剂师的干预显著减少了重症监护室 (ICU) 退院后不适当的抗精神病药物持续使用. 这提高了在护理过渡期间的药物安全性.
科学领域:
- 药理学 药理学是指药理学的学科.
- 患者安全 患者安全
- 医疗保健管理的管理
背景情况:
- 护理过渡 (TOC) 是潜在的药物错误的关键点.
- 重症监护室 (ICU) 需要有效的TOC,特别是用于激动,妄想和镇静的抗精神病药物等药物.
- 在ICU中使用抗精神病药物需要在护理过渡期间进行谨慎管理.
研究的目的:
- 设计,实施和评估药剂师干预措施,旨在减少不适当的抗精神病药物从ICU继续使用.
- 评估干预对接受抗精神病药物出院的患者的影响以及药剂师干预的接受率.
- 在 ICU 后的护理过渡期间提高药物安全性.
主要方法:
- 在社区医院的历史控制组进行前性研究.
- 包括接受了ICU的成人患者,并为激动,妄想或镇静处方了一种抗精神病药物.
- 历史对照组和干预组之间的抗精神病药物持续率的比较.
主要成果:
- 干预组显示抗精神病药物持续超过ICU转移72小时的比例明显较低 (16.7%与57.6%,P=0.002).
- 与历史组相比,干预组的患者在不适当的抗精神病药物下出院的患者较少 (12.5%与36.4%,P=0.04).
- 药剂师的干预证明了在护理过渡期间对药物管理的显著积极影响.
结论:
- 药剂师驱动的干预有效地减少了ICU出院后继续服用抗精神病药物的情况.
- 这项干预措施提高了在ICU后72小时的药物安全性,以及在出院时的药物安全性.
- 这突出了药剂师在优化在重症监护过渡期间药物使用的关键作用.
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