来自捐赠者的感染-来自新加坡,日本和泰国的见解
Sophie Seine Xuan Tan1,2, Pakpoom Phoompoung3, Koh Okamoto4
1Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore.
概括
固体器官移植 (SOT) 中的捐赠者衍生的感染 (DDI) 是亚洲的一个担忧. 目前的查有所不同,监测和报告存在差距,突出了协调努力和DDI注册表的需要.
科学领域:
- 移植医学 移植医学
- 传染性疾病 传染性疾病
- 公共卫生政策 公共卫生政策
背景情况:
- 固体器官移植 (SOT) 已经在亚洲显著扩张.
- 供体感染 (DDI) 对移植结果构成相当大的风险.
- 了解和缓解DDI对于改善该地区的SOT至关重要.
研究的目的:
- 审查监管框架,查协议和对亚洲国家/地区的DDI的管理实践.
- 确定DDI监督和控制的当前做法和未满足的需求.
- 提供来自新加坡,日本和泰国的见解.
主要方法:
- 从亚洲各地的传染病专家收集有关SOT数量和DDI发病率的数据.
- 审查国家监管框架和捐赠者/接受者查协议.
- 来自新加坡,日本和泰国的数据呈现.
主要成果:
- 在所有被审查的国家,对艾滋病毒,乙型肝炎,乙型肝炎和梅毒进行强制性查.
- 日本独特地对HTLV-1进行查;新加坡实施对登革热,寨卡和奇孔古尼亚的普遍查.
- 在DDI监测和报告中存在显著的差距,未知和可能报告不足的发病率.
结论:
- 新加坡,日本和泰国的现行做法为DDI管理提供了宝贵的见解.
- 亚洲急需一个DDI注册表.
- 协调的区域努力对于解决固体器官移植中的DDI至关重要.
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