国家对纳洛联合处方的授权与纳洛联合处方的短期增加有关
Huiru Dong1, Erin J Stringfellow2, Alton Russell3
1Huiru Dong, Harvard University, Boston, Massachusetts.
Health affairs (Project Hope)
|September 3, 2024
概括
国家规定增加了对高风险患者的纳洛 (过量逆转药物) 共同处方. 然而,随着时间的推移,这种效应在几个州减少了,这表明单独授权可能无法确保持续减少过量使用风险.
科学领域:
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
- 卫生政策 卫生政策
背景情况:
- 美国阿片类药物危机需要制定战略来减少过量死亡.
- 纳洛联合处方的任务旨在增加高危患者获得过量逆转药物的机会.
- 鉴定风险人群包括那些使用高阿片类药物剂量,使用二类药物或有物质使用障碍/过量使用史的人群.
研究的目的:
- 调查任务实施后高风险患者中纳洛联合处方率的变化.
- 评估州级纳洛联合处方授权对过量风险减轻的纵向影响.
主要方法:
- 对接受处方阿片类药物 (2016-2021) 的全国性多病患者队列的分析.
- 控制中断时间序列分析,以评估十个实施国家的任务效应.
- 专注于确定患有过量服用风险较高的患者.
主要成果:
- 在执行任务后,在十个州中的八个州观察到纳洛联合处方的显著立即增加.
- 在最初的上升之后,这些州中的五个州注意到了代码发放率的下降趋势.
- 在不同州的任务有效性和可持续性的变化.
结论:
- 国家授权最初可以促进对处于风险的阿片类药物使用者的纳洛联合处方.
- 单靠授权可能不足以实现纳洛获取持续增加.
- 需要采取额外的战略来增强和维持任务在解决过量危机方面的影响.
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