神经超声波,以检测患有外围神经病变的患者内在神经微血管性
Toshiyuki Hayashi1, Noriko Matsumoto1, Seira Hatake1
1Department of Neurology, Nippon Medical School, Tokyo, Japan.
概括
神经超声波显示,在炎症性神经病变中,微血管流量增加. 这一发现可能有助于通过识别脑内神经超血管化来诊断外围神经病变.
科学领域:
- 神经学 神经学
- 医疗成像医学成像
- 血管生物学 血管生物学
背景情况:
- 周围神经病变包括影响神经功能的各种疾病.
- 评估外围神经中的微血管变化对于诊断至关重要.
- 神经超声波提供了一种非侵入性方法来评估神经结构.
研究的目的:
- 用神经超声波来评估患有外围神经病变的患者外围神经内的微血管流动.
- 根据神经内脉血流模式,区分炎症性和非炎症性神经病变.
- 探索神经超声波在外围神经病变中的诊断效用.
主要方法:
- 连续的患有外围神经病变的患者被分为炎症和非炎症组.
- 神经大小和神经内血流被评估在中枢和部神经.
- 使用了先进的成像技术,包括彩色多普勒,先进的动态流量 (ADF) 和卓越的微血管成像 (SMI).
主要成果:
- 这项研究包括39名患者.
- 与彩色多普勒 (5/39) 和ADF (5/39) 相比,使用SMI (13/39) 的患者中检测到更高比例的内耳血流.
- 在炎症性神经病变 (54.2%) 与非炎症性神经病变 (0%,p=0.0005) 之间,内耳血流显著增加.
结论:
- 内神经高血管化在炎症性外围神经病变中更为普遍.
- 神经超声波,特别是像SMI这样的先进技术,可以检测到外围神经中的微血管变化.
- 使用神经超声波评估微血管流动,可以作为对外围神经病变的有价值的诊断工具.
相关概念视频
Local Anesthetics: Differential Sensitivity of Nerve Fibers
Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...


