上肢深静脉血栓症:发生率,危险因素和化学预防的有效性
Caroline K Olt1, Bo Hu2, Michael B Rothberg3
1From the Department of Internal Medicine.
Southern medical journal
|September 3, 2024
概括
上肢深静脉血栓塞 (UEDVT) 是罕见的,但像中央静脉导管这样的危险因素增加了发病率. 药物预防与UEDVT发展风险降低有关.
科学领域:
- 医学研究 医学研究
- 临床流行病学临床流行病学
- 血栓形成的原因之一是血栓形成.
背景情况:
- 上肢深静脉血栓塞 (UEDVT) 带来风险,包括肺栓塞.
- 目前的指导方针缺乏针对UEDVT预防的具体建议.
- 了解UEDVT发生率和风险因素对于预防至关重要.
研究的目的:
- 确定UEDVT的发病率和确定风险因素.
- 评估药理学预防在预防UEDVT时的有效性.
主要方法:
- 对超过194,000名成年患者的回顾性队列研究,这些患者被录入克利夫兰诊所医院 (2011-2019).
- 排除标准包括以前的VTE,短期停留或治疗性抗凝药.
- 多变量后勤回归分析了风险因素和预防与UEDVT的关联.
主要成果:
- 无线静脉动脉瘤的发病率为0.25% (496名患者),占所有静脉动脉瘤的36.8%.
- 关键的风险因素包括外围插入的中央导管 (OR 4.62) 和中央静脉导管 (OR 3.57).
- 药物预防表明与UEDVT发展有负面关联 (OR 0.72).
结论:
- 虽然UEDVT不常见,但某些患者群体面临更高的风险.
- 建议将UEDVT风险因素纳入VTE风险评估模型.
- 鉴定出高风险患者应考虑进行化疗预防.
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