血糖状况和对死亡率的影响:芬兰初级保健中心血管疾病的多因素预防计划
Susanna M Kuneinen1, Hannu Kautiainen2, Mikael O Ekblad3
1Department of General Practice, University of Turku and Turku University Hospital, Turku, Finland; Pihlajalinna Plc, Finland.
Primary care diabetes
|September 3, 2024
概括
通过查检测出糖尿病的个体面临着明显更高的死亡风险,即使在干预后. 癌症现在是这些患者的主要死亡原因,从心血管疾病转移.
科学领域:
- 心血管疾病流行病学
- 糖尿病研究研究 糖尿病研究
- 公共卫生查计划 公共卫生查计划
背景情况:
- 基于社区的查计划对于识别有风险的个体至关重要.
- 血糖状况显著影响长期健康结果.
- 早期检测和干预是管理糖尿病和糖尿病前期的关键.
研究的目的:
- 为了在正常血糖,糖尿病前期和糖尿病患者中比较13年全因死亡率.
- 在社区查计划中评估血糖状况对死亡率的影响.
- 分析与血糖状况相关的死亡原因.
主要方法:
- 一项人口调查确定了2569名年龄在45-70岁之间的参与者,没有先前存在的心血管疾病或糖尿病.
- 口服葡萄糖耐受性测试确定了血糖状况 (正常血糖,糖尿病前期,糖尿病).
- 提供了多因素干预,并追踪了13年的死亡率,调整了各种风险因素.
主要成果:
- 与正常血糖患者相比,糖尿病前期患者的死亡风险增加了1.34倍 (HR: 1.34; 95% CI: 0.98-1.83),而糖尿病患者的死亡风险增加了2.31倍 (HR: 2.31; 95% CI: 1.62-3.31).
- 标准化死亡率在正常血糖组为0.63,糖尿病前组为0.91,糖尿病组为1.55.
- 癌症占死亡人数的42%,其次是心血管疾病占28%.
结论:
- 检测到的糖尿病显著增加死亡风险,即使有初级保健干预.
- 这些人的首要死亡原因已经转向了癌症.
- 血糖状况是通过社区查确定的个人长期生存的关键决定因素.
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