器官移植接收者对COVID-19疫苗接种的看法
River Lerner1, Panos Arvanitis2, Dorra Guermazi3
1The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Program in Liberal Medical Education, Brown University, Providence, Rhode Island.
Transplantation proceedings
|September 3, 2024
概括
器官移植接受者对COVID-19疫苗的犹受到政治信仰和65岁以上的家庭成员的影响. 了解这些因素可以提高疫苗的接受率,并为这个脆弱的人群量身定制干预措施.
科学领域:
- 移植医学 移植医学
- 疫苗学 疫苗学 疫苗学
- 行为科学是一种行为科学.
背景情况:
- 器官移植接受者 (OTRs) 从COVID-19疫苗接种中获得了减弱但明显的好处.
- 了解OTRs的疫苗犹对于公共卫生战略至关重要.
- 需要有针对性的干预措施来改善这种免疫受损群体的疫苗接种.
研究的目的:
- 评估成年器官移植接受者接受COVID-19疫苗的情况.
- 确定与OTRs疫苗犹相关的社会人口统计学和医学因素.
- 引入和验证疫苗接受综合评分 (VACS) 作为疫苗信心的衡量标准.
主要方法:
- 一项针对成年OTR的调查收集了社会人口统计,病史和疫苗值的数据.
- 疫苗接受综合评分 (VACS) 是作为七个疫苗信心领域的平均利克特评分而开发的.
- 计算了不变的几率比率和AUC值,以检查与VACS和疫苗坚持的关联.
主要成果:
- 在46名OTR中,32.6%是女性,13.3%是黑人,6.77%是西班牙裔/拉丁裔/a/x;中位数年龄为58.
- 担忧包括疫苗风险 (46.3%),全移植效应 (47.6%) 和政府动机 (55.6%).
- 政治保守主义与较低的VACS相关,而与≥65岁的个人生活与较高的VACS相关. 较高的VACS与≥3-4次COVID-19免疫接种有关.
结论:
- 政治信仰和老年家庭成员是OTRs疫苗接受的关键相关因子.
- 该VACS可以标准化疫苗研究中的分析,并识别有风险的个体.
- 定制的宣传和教育可以解决OTRs的疫苗犹,改善公共卫生结果.
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