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在T-ALL中具有抗弗拉特基德的CD7-CAR T细胞

Bernice L Z Oh1,2, Noriko Shimasaki2, Elaine Coustan-Smith2

  • 1Viva-University Children's Cancer Center, Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore, Singapore.

Nature medicine
|September 3, 2024
PubMed
概括

化学抗原受体 (CAR) 向CD7的T细胞对复发性或耐火性T细胞急性淋巴细胞白血病 (T-ALL) 有希望. 这种疗法实现了高缓解率与可控毒性,为难以治疗的T-ALL提供了新的治疗途径.

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Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
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