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Updated: Jun 14, 2025

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酵母EndoG通过降解核外DNA物种来防止基因组不稳定

Yang Yu1, Xin Wang2,3, Jordan Fox1

  • 1Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX, USA.

Nature communications
|September 3, 2024
PubMed
概括

像Nuc1这样的酵母核酶通过降解细胞质DNA来防止核基因组的不稳定性. 这一过程限制了线粒体DNA (mtDNA) 和逆转移子cDNA的插入,从而保持了基因组的完整性.

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