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基于药理动力学模型的评估,对严重血友病B的因子IX预防治疗方案进行评估

Björn Vandewalle1, Giancarlo Castaman2, Maria Teresa Álvarez-Román3

  • 1Exigo Consultores, Lisbon, Portugal.

Scientific reports
|September 3, 2024
PubMed
概括

这项研究使用药理动力学建模对血友病B的因子IX (FIX) 产品进行了比较. 结果显示,在最佳剂量方面存在显著差异,rIX-FP在较低剂量时提供更高的水平,N9-GP在成人中显示消耗减少.

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