氧化与芬太尼在腹腔镜性肌肉切除术后患者控制的静脉静脉止痛的作用:单盲随机对照试验
Ping Dong1, Xiaoli Qu2, Yue Yang1
1Department of Anesthesiology, Qilu Hospital, Shandong University, Jinan, 250012, Shandong Province, China.
Scientific reports
|September 3, 2024
概括
氧化和芬太尼在腹腔镜瘤切除术后提供类似的疼痛缓解. 然而,氧化导致患者满意度更高,头痛更少,使其成为术后疼痛管理的首选.
科学领域:
- 麻醉学和疼痛管理
- 妇科外科手术 妇科外科
- 药理学 药理学是指药理学的学科.
背景情况:
- 手术后的疼痛管理对于腹腔镜瘤切除术后的恢复至关重要.
- 患者控制的静脉注射止痛疗法 (PCIA) 是一种常见的手术疼痛管理方法.
- 比较像氧化和芬太尼这样的阿片类止痛药对于优化患者的治疗结果至关重要.
研究的目的:
- 为了比较氧化与芬太尼在腹腔镜瘤切除术后的PCIA的疗效和安全性.
- 评估两组止痛药之间的患者满意度和不良事件,特别是头痛的发生率.
主要方法:
- 一个单盲,随机对照试验,涉及60名参与者接受了腹腔镜性肌肉切除术.
- 患者通过PCIA接受了氧化或芬太尼.
- 疼痛强度使用数值评分表 (NRS) 在休息和运动期间进行评估.
- 术后记录了患者的满意度和不良事件.
主要成果:
- 氧化和芬太尼都提供了可比的疼痛缓解,在不同术后时间点的NRS得分没有显著差异.
- 与芬太尼尔组 (36.7%) 相比,氧化组 (73.3%) 的患者满意度显著更高.
- 手术后48小时内头痛的发生率在氧化组比芬太尼组低.
结论:
- 氧化可提供类似的术后疼痛缓解,以芬太尼在腹腔镜瘤切除术后.
- 与芬太尼相比,oxycodone在这种手术背景下显示出更高的患者满意度和更低的头痛发病率.
- 氧化是一种可行的和潜在的可取选择PCIA在患者进行腹腔镜瘤切除术.
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