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Updated: Jun 6, 2026

Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation
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从空间解析的转录组学数据绘制细胞相互作用的地图.

James Zhu1, Yunguan Wang1,2,3, Woo Yong Chang1

  • 1Quantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Nature methods
|September 3, 2024
PubMed
概括

Spacia是一个新的框架,使用空间转录学来分析细胞之间的通信. 它克服了现有工具的局限性,使细胞之间基因表达相互作用的更准确的映射成为可能.

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相关概念视频

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...