在急性前列腺切除术后,Nomogram预测了早期的尿失禁.
Cheng Shen1,2, Xu Zhu1,3, Zhan Chen1,2
1Department of Urology, Affiliated Hospital 2 of Nantong University, Nantong, China.
BMC cancer
|September 3, 2024
概括
这项研究开发了一种名谱,用于预测激进前列腺切除术 (RP) 后的早期尿失禁. 该工具可以识别高风险患者,帮助预防前列腺切除术后失禁的预防措施.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术瘤学手术瘤学
- 医疗信息学 医疗信息学
背景情况:
- 尿失禁是急性前列腺切除术 (RP) 后的常见副作用.
- 没有完全了解RP后失禁的确切原因和恢复模式.
- 识别风险因素对于管理和潜在地预防早期失禁至关重要.
研究的目的:
- 为了确定RP后早期尿失禁的风险变量.
- 开发一个预测工具,结合手术前的泌尿动力学发现.
- 为指导旨在减少早期前列腺切除术后失禁发生率的临床干预措施.
主要方法:
- 对接受RP的142名患者的回顾性分析.
- 单变量和LASSO逻辑回归用于风险因素识别.
- 开发和内部验证预测早期 incontinence 风险的 nomogram.
- 使用c指数,ROC曲线,校准图表和决策曲线分析评估模型性能.
主要成果:
- 确定了7个早期尿失禁的独立风险因素.
- 在这些因素的基础上构建了一个名ogram,证明了高精度和稳定性.
- 该模型在培训和验证队伍中显示出优异的歧视和校准.
- 决策曲线分析证实了名图的临床实用性.
结论:
- 开发的诺米图提供了准确的,个性化的风险评估,用于RP后的早期尿失禁.
- 该工具可以帮助识别高风险个体并实施有针对性的预防策略.
- 诺米图支持临床决策,用于管理前列腺切除术后的尿失禁.
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