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Updated: Jun 14, 2025

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
00:06

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

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一种功能变体rs912304用于晚发型T1D风险,通过调节亲炎性细胞因子响应基因STXBP6表达来促进小岛功能障碍

Yu Qian1, Shu Chen1,2, Yan Wang1

  • 1Department of Endocrinology and Metabolism, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.

BMC medicine
|September 3, 2024
PubMed
概括

一种遗传变异 (rs912304) 与晚发型1型糖尿病 (T1D) 风险有关,并影响小岛功能. 这一发现揭示了T1D病原体和潜在的治疗点.

关键词:
小岛的自身免疫力岛屿功能 岛屿功能在SXBp6中使用.在T1D中,它是T1D.变种 变种 变种 变种

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