在慢性病中,BRCC36调节β-catenin的全方位化,以缓解血管化

Yalan Li1, Xiaoyue Chen1, Yiqing Xiong1

  • 1Department of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing, #300 Guangzhou Road, 210029, China.

PubMed
概括

含BRCA1/BRCA2复杂子单元36 (BRCC36) 通过抑制Wnt/β-catenin通路,在慢性病 (CKD) 中保护血管化 (VC). 抑制BRCC36可能为CKD患者的VC提供一种新的治疗策略.

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