增加的包装细胞体积改变了马匹的粘弹性凝固参数的护理点
Rebecca C Bishop1, Kaitlyn M Jonk1, Alessandro Migliorisi1
1Department of Veterinary Clinical Medicine, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.
Equine veterinary journal
|September 4, 2024
概括
在使用烯的马中诱导的多细胞血症导致VCM VetTM装置上的异常粘弹性凝血痕迹. 基于等离子体的凝血测试和血小板计数没有受到影响,这表明在多细胞血症期间评估凝血的潜在限制.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 关键的护理关键的护理
- 血液学 血液学 血液学
- 凝血生理学 凝血生理学
背景情况:
- 多细胞血症和凝血病是影响严重疾病马匹生存率的关键危险因素.
- 准确的凝血评估对于马的重症监测至关重要,但多细胞血症可能会干扰结果.
研究的目的:
- 调查诱导多细胞血症对VCM VetTM粘弹性凝血装置测量的凝血参数的影响.
- 为了确定烯诱导的多细胞血症是否会影响马匹的护理点粘弹性测试.
主要方法:
- 一项前性干预研究,涉及七只健康的成年马.
- 过渡性多细胞血症是使用静脉注射利来诱导的.
- 凝血参数 (VCM VetTM,PT,PTT),包装细胞体积 (PCV) 和总固体在输液后的基线,5分钟和2小时被测量.
主要成果:
- 烯诱导了显著的缩和过渡性多细胞血症,由增加的PCV证明.
- 在VCM VetTM装置上的粘弹性痕迹 (A10,A20) 显示出在多细胞血症期间的低凝血模式.
- 基于血的凝血测试 (PT,PTT) 和血小板计数没有受到诱导的多细胞血症的影响.
结论:
- 马的诱导性多细胞血症与使用VCM VetTM装置的改变粘弹性凝血测量有关.
- 该研究强调了多细胞血症期间粘性弹性和基于血的凝血评估之间的潜在差异.
- 需要进一步的研究,以了解粘弹性测试对患有多细胞血症的马的临床影响.
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