骨髓灰质炎和COVID-19:一个系统审查和元分析
Amirhossein Nafari1, Seyedpouzhia Shojaei2, Reza Jalili Khoshnood3
1Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Basic and clinical neuroscience
|September 4, 2024
概括
在肌痛性骨髓灰质炎 (MG) 患者中,COVID-19感染的综合流行率为2%. 这次系统性审查和元分析分析了18项研究,以确定MG患者的COVID-19感染率.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 自身免疫性疾病 自身免疫性疾病
背景情况:
- 骨髓灰质炎 (MG) 是一种自身免疫性神经肌肉结合障碍.
- 在MG患者中,COVID-19感染率因研究而异.
- 了解MG中的COVID-19流行率对于患者管理至关重要.
研究的目的:
- 为了估计COVID-19感染在患有骨髓质疏松症的个体中的综合流行率.
- 综合现有的关于MG患者COVID-19的研究.
主要方法:
- 在PubMed,Scopus,EMBASE,Web of Science,Google Scholar和灰色文学中进行系统的文献搜索,截至2021年10月.
- 从最初的253件中删除重复件后,包括18件物品.
- 数据提取包括参与者数量,MG患者数量,症状,住院和死亡率.
主要成果:
- 在MG患者中,COVID-19感染的综合流行率为2% (95% CI,1%-3%).
- 感染MG患者的住院患病率为43% (95%CI,26-60%).
- MG恶化发生率为33% (95% CI,20%-46%).
结论:
- 在患有骨髓灰质炎的个体中,COVID-19感染的综合流行率为2%.
- 许多患有COVID-19的MG患者经历了住院治疗和疾病恶化.
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