在患有肺高血压的患者中,用于纯原生大动脉吐的跨导管大动脉置换的结果
Da-Wei Lin1,2, Zi-Long Weng1,2, Jia-Ning Fan1,2
1Department of Cardiology, Zhongshan Hospital, Fudan University, 200032 Shanghai, China.
Reviews in cardiovascular medicine
|September 4, 2024
概括
过导管大动脉置换 (TAVR) 对于患有肺高血压 (PH) 的纯原生大动脉吐 (PNAR) 患者来说是安全有效的. 在不增加不良事件的情况下,TAVR可降低大动脉反和PH.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 心脏外科手术 心脏外科手术
背景情况:
- 严重的大动脉反 (AR) 经常与肺高血压 (PH) 并存.
- 过导管大动脉置换 (TAVR) 是纯原生大动脉吐 (PNAR) 的关键治疗方法.
- 了解PH的PNAR患者的TAVR结果至关重要.
研究的目的:
- 评估TAVR在PNAR患者的短期疗效和安全性,同时患有PH.
- 为了比较经过TAVR的PNAR患者与没有PH患者之间的结果.
主要方法:
- 对接受TAVR的103名PNAR患者进行了回顾性研究 (2018年6月-2023年6月).
- 根据肺动脉静脉压 (PASP) 将患者分为具有或没有PH的组.
- 收集了基线特征,成像和后续数据.
主要成果:
- 在103名患者中,有48名患者患有PH,呈现出较高的STS得分,功能障碍和高NT-proBNP.
- 在PH患者中,LVEF降低,LV尺寸更大,三腹反 (TR) 增加.
- 在两组中,TAVR显著降低了PASP,额头回 (MR) 和TR,不良事件没有差异.
结论:
- 对于PH的PNAR患者来说,TAVR是一种安全有效的选择.
- 该程序成功地减少了大动脉反和肺高血压.
- 在这个患者队列中,TAVR不会增加术后并发症的风险.
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