Search research articles

关于 JoVE

概览领导团队博客 JoVE 帮助中心

作者

出版流程编辑委员会范围与政策同行评审常见问题投稿

图书馆员

用户评价订阅访问资源图书馆顾问委员会常见问题

研究

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments 存档

教育

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual 教师资源中心教师网站

使用条款与条件

相关概念视频

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序

Same author

Actin depolymerization promotes axon regeneration by restoring axonal mitochondrial transport in mouse models of optic neuropathy.

Science translational medicine·2026

Same author

Glaucoma Classification Through SSVEP-Derived ON- and OFF-Pathway Features.

Translational vision science & technology·2026

Same author

Evidence That Cerebral Visual Impairment May Evolve after Initial Brain Injury.

Ophthalmology·2026

Same author

Steady-state EEG captures how elementary classroom instruction drives plasticity for novel visual words.

NPJ science of learning·2025

Same author

Strong mnemonic prediction errors increase cognitive control, attention, and arousal.

bioRxiv : the preprint server for biology·2025

Same author

Cortical latency predicts reading fluency from late childhood to early adolescence.

Developmental cognitive neuroscience·2025

Search research articles

相关实验视频

Updated: Jun 14, 2025

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

通过SSVEP衍生的ON和OFF路径特征来分类青光眼.

Martin T W Scott¹, Hui Xu², Alexandra Yakovleva³

¹Department of Psychology, Stanford University.

medRxiv : the preprint server for health sciences

|September 4, 2024

概括

此摘要是机器生成的。

这种OFF路径在格洛科马中显示出更大的脆弱性. 与ON路径测量相比,OFF路径稳定状态视觉唤起潜力 (SSVEP) 测量在诊断青光眼方面略有改善.

更多相关视频

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Published on: May 12, 2019

Objectively Assessing Sports Concussion Utilizing Visual Evoked Potentials

Objectively Assessing Sports Concussion Utilizing Visual Evoked Potentials

Published on: April 27, 2021

相关实验视频

Last Updated: Jun 14, 2025

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Published on: May 12, 2019

Objectively Assessing Sports Concussion Utilizing Visual Evoked Potentials

Objectively Assessing Sports Concussion Utilizing Visual Evoked Potentials

Published on: April 27, 2021

科学领域:

眼科医生眼科眼科
神经科学是一个神经科学.
视觉电生理学视觉电生理学

背景情况:

人们越来越认识到视网膜的OFF路径比ON路径更容易受到青光眼损伤.
视觉功能评估的OFF-pathway具有早期青光眼诊断的潜力.
稳态视觉唤起潜力 (SSVEP) 提供了一种非侵入性方法来测量视觉功能.

研究的目的:

调查OFF-pathway和ON-pathway偏差的SSVEP测量是否可以差异地预测青光眼的诊断.
在大型队列中,比较OFF路径与ON路径SSVEP特征的诊断预测准确度.

主要方法:

使用后勤回归与k倍交叉验证和随机森林分类器.
分析了98名青光眼患者和71名对照患者的SSVEP测量结果,包括ON和OFF路径偏差.
包括一套全面的响应特征和来自参与者的双眼数据.

主要成果:

与ON-pathway特征相比,OFF-pathway偏差特征显示了对青光眼诊断的预测准确度的边际增强.
开发的分类器的性能低于之前使用孤立检查VEP的一些研究,可能是由于每个参与者的数据较小,并且在之前的工作中没有分列训练测试.
尽管存在局限性,但该研究发现了OFF途径功能生物标志物的潜力,可用于青光眼诊断.

结论:

偏离路径的SSVEP测量结果显示,对青光眼的诊断有希望,尽管有轻微的改善.
需要进一步的研究来探索和完善OFF路径的功能生物标志物,以改善青光眼的检测.
这些发现支持继续调查视网膜OFF通路在眼科中的诊断实用性.