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Updated: Jun 14, 2025

Array Comparative Genomic Hybridization Array CGH for Detection of Genomic Copy Number Variants
09:16

Array Comparative Genomic Hybridization Array CGH for Detection of Genomic Copy Number Variants

Published on: February 21, 2015

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对帕金森病拷贝数变异的全基因组关联研究

Zied Landoulsi1,2, Ashwin Ashok Kumar Sreelatha3, Claudia Schulte4,5

  • 1Luxembourg Centre for Systems Biomedicine, University of Luxembourg; L-4367, Esch-sur-Alzette, Luxembourg.

medRxiv : the preprint server for health sciences
|September 4, 2024
PubMed
概括

副本数变异 (CNVs) 显著影响帕金森病 (PD) 的病原性. 这项研究发现PD患者的CNV负担更高,特别是PRKN基因,与早期发病PD (EOPD) 的早期疾病发病有关.

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相关概念视频

Comparing Copy Number Variations and SNPs02:26

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Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
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