在AWI-Gen项目中计算社会经济地位
Scott Hazelhurst1,2, Palwendé Boua3,1, Ananyo Choudhury1
1Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg.
medRxiv : the preprint server for health sciences
|September 4, 2024
概括
这项研究详细介绍了Africa Wits INDEPTH基因组和环境研究伙伴关系 (AWI-Gen) 如何利用四个非洲国家超过12,000名参与者的资产所有权数据计算社会经济地位.
科学领域:
- 公共卫生 公共卫生
- 基因组学就是基因组学.
- 流行病学 流行病学
背景情况:
- 社会经济地位 (SES) 在公共卫生,流行病学和全基因组关联研究中至关重要.
- 在研究中,SES被用作直接测量或共变量.
- 非洲Wits INDEPTH基因组和环境研究伙伴关系 (AWI-Gen) 专注于基因组和环境对非传染性疾病的影响,特别是心脏代谢条件.
研究的目的:
- 在AWI-Gen项目中描述计算社会经济地位 (SES) 的方法.
- 概述从资产所有权数据中推导SES的过程.
- 为非洲大规模研究中SES评估提供标准化的方法.
主要方法:
- 在AWI-Gen.的第一阶段,从大约12,000名参与者那里收集了资产所有权数据.
- 在四个非洲国家的六个地点招募了参与者.
- 开发了一种特定的算法,以基于资产登记册计算SES.
主要成果:
- 在AWI-Gen第一阶段,成功收集了全面的资产所有权数据.
- 从这些资产数据中获得了社会经济地位的可计算指标.
- 该方法为AWI-Gen队列中的SES分析提供了基础.
结论:
- 在AWI-Gen项目建立了一个强大的方法来评估社会经济地位使用资产数据.
- 本技术说明是SES计算在类似研究环境中的指南.
- 准确的SES测量对于了解非洲的健康差异和疾病病因至关重要.
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