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Updated: Jun 14, 2025

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受体激活器NF-κB (RANK) 基因促进区的CpG甲基化划定了与衰老相关的RANK基因表达的减少

Riko Kitazawa1,2, Ryuma Haraguchi1, Yuki Murata1

  • 1Department of Molecular Pathology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.

Acta histochemica et cytochemica
|September 4, 2024
PubMed
概括

与年龄相关的DNA甲基化减少了骨质细胞前体中的受体激活剂NF-κB (RANK) 基因表达. 这种表观遗传变化通过损害骨形成,有助于老年骨质疏松症的发展.

关键词:
通过DNA甲基化.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.骨质细胞的骨质细胞.衰老是一种老化.年老的骨质疏松症

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