减少艾滋病毒阳性患者的药物错误:临床药剂师的影响
Elmien Bronkhorst1, Michè Joseph-Busby1, Selente Bezuidenhout2
1Department of Clinical Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
Southern African journal of HIV medicine
|September 4, 2024
概括
药剂师在住院艾滋病毒感染者 (PLHIV) 中发现了466种药物错误. 药剂师的参与在24小时内解决了超过一半的ME,改善了患者的护理.
科学领域:
- 临床药房 临床药房
- 药物监督 药物监督 药物监督
- 艾滋病毒 医学 艾滋病毒 医学
背景情况:
- 抗逆转录病毒疗法增加了艾滋病毒感染者 (PLHIV) 的预期寿命.
- 预期寿命的增加导致更多的PLHIV因非传染性疾病住院治疗.
- PLHIV患者住院治疗增加了药物错误 (ME) 的风险.
研究的目的:
- 确定艾滋病毒感染者住院患者 (PLHIV) 药物错误 (MEs) 的流行率和类型.
- 突出临床药剂师在识别和解决ME的关键作用.
- 量化药剂师干预对ME解决方案的影响.
主要方法:
- 一项为期14周的前性观察性研究,涉及180名住院的PLHIV患者.
- 药剂师审查患者档案,使用数据收集仪器识别ME.
- 关于ME的文档,建议的干预措施和解决状态.
主要成果:
- 总共有466个ME在180个患者档案 (453个评论) 中被确定.
- 最常见的ME包括错过剂量 (57.1%) 和错误的剂量 (22.2%).
- 药剂师的干预导致58.2%的ME在24小时内得到解决.
结论:
- 住院艾滋病毒感染者 (PLHIV) 经历了大量的药物错误 (ME).
- 临床药剂师对于在这个脆弱人群中检测和纠正ME至关重要.
- 药剂师主导的干预措施通过减少ME显著改善了患者的治疗结果.
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