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Updated: Jun 14, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers

Published on: September 20, 2018

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SWI/SNF PBAF复合物促进了镇压性染色质的REST占用

Elena Grossi1,2,3, Christie B Nguyen1,2,3,4, Saul Carcamo3,5

  • 1Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

bioRxiv : the preprint server for biology
|September 4, 2024
PubMed
概括

聚菌相关的BAF (PBAF) 染色体重塑复合物有助于使黑色素瘤中的神经元基因沉默. 失去ARID2会破坏PBAF,导致这些基因在患者中的表达增加.

关键词:
在 ARID2 的 ARID2 里面.这就是PBAF的PBAF.休息时间 休息时间在 SWI/SNF 中.黑色素瘤是一种黑色素瘤.

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