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Updated: Jul 23, 2026

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快速在位形成PEG水凝用于粘膜药物输送

Taj Yeruva1, Robert J Morris2, Luke Zhao1

  • 1Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA.

bioRxiv : the preprint server for biology
|September 4, 2024
PubMed
概括

这项研究引入了一种新的聚乙烯糖醇 (PEG) 水凝,该水凝快速在位形成,粘附于粘膜组织,并提供持续的药物输送. 这些生物可降解的凝在粘膜部位提供了改善的治疗保留和疗效.

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Pore Transport and Ion-Pair Transport01:17

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Pore transport and ion-pair formation are critical mechanisms for the absorption and distribution of drugs in the body.
Pore transport, also known as convective transport, is a process where small molecules like urea, water, and sugars rapidly cross cell membranes as though there were channels or pores in the membrane. Although direct microscopic evidence is limited  but the concept of pores or channels is widely accepted based on physiological evidence. Despite the lack of direct microscopic...