人类健康的下一代益生菌:一个新兴的前景
Tawseefa Jan1, Rajeshwari Negi2, Babita Sharma3
1Department of Food Technology, Dr. Khem Singh Gill Akal College of Agriculture, Eternal University, Baru Sahib, Sirmaur, Himachal Pradesh, India.
Heliyon
|September 4, 2024
概括
下一代益生菌 (NGP) 提供健康益处,但面临生产挑战. 本综述涵盖了它们对市场商业化的影响,监管和风险.
科学领域:
- 微生物学 微生物学
- 胃肠病学 胃肠病学
- 生物技术是生物技术.
背景情况:
- 人的肠道微生物群在宿主健康中起着至关重要的作用.
- 下一代益生菌 (NGP) 是具有治疗潜力的有益的肠道微生物.
- 在NGP生产中存在挑战,包括营养需求和氧气敏感性.
研究的目的:
- 为下一代益生菌提供全面的概述.
- 讨论它们的健康益处,监管格局和风险评估.
- 确定食品和制药行业商业化标准.
主要方法:
- 关于下一代益生菌的科学出版物的文献综述.
- 对健康益处,技术障碍和监管考虑的分析.
- 对潜在的NGP候选人的风险评估评估.
主要成果:
- 这些NGP候选物包括Bacteroides,Faecalibacterium,Akkermansia和Clostridium等属.
- 与传统的益生菌不同,一些NGP,如Bacteroides和Clostridium,可能具有模两可的传染病潜力.
- 在NGP生产中的技术障碍需要先进的交付系统.
结论:
- 下一代益生菌作为生物疗法和补充剂具有显著的前景.
- 解决生产挑战和进行彻底的风险评估对于NGP商业化至关重要.
- 监管框架需要适应NGP的独特特征,以便安全进入市场.
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