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Updated: Jun 14, 2025

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用于分子成像和疾病诊断的酶响应型多锁光学探头

Penghui Cheng1, Kanyi Pu1,2

  • 1School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 70 Nanyang Drive, 637457 Singapore, Singapore. kypu@ntu.edu.sg.

Chemical Society reviews
|September 4, 2024
PubMed
概括

多锁可激活光学探头 (MOP) 通过检测多个生物标志物,比单锁探头提供更好的疾病诊断特异性. 这提高了图像导向治疗的准确性和有效性,降低了毒性.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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