打和白天嗜睡与随后的高血压事件的关联:基于人口的队列研究
Pauline Balagny1,2, Emmanuelle Vidal-Petiot2,3, Sofiane Kab1
1Université Paris Cité, Paris Saclay University, Université de Versailles Saint-Quentin-en-Yvelines, Institut National de la Santé et de la Recherche Médicale (INSERM), Unité Mixte de Service 011 Population-based Cohorts Unit, France (P.B., S.K., M.G., M.Z., E.W.).
Hypertension (Dallas, Tex. : 1979)
|September 4, 2024
概括
打和过度的白天嗜睡会增加患高血压的风险. 这些症状在阻塞性睡眠呼吸暂停中很常见,可以作为初级保健中高血压预防的查工具.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 阻塞性睡眠呼吸暂停与高血压有关,但症状特异性的风险尚不清楚.
- 调查打和嗜睡作为新发高血压的预测因素的前性研究.
研究的目的:
- 为了确定打和白天嗜睡是否与事件高血压有关.
- 评估症状频率和高血压风险之间的剂量依赖关系.
主要方法:
- 法国CONSTANCES队列数据 (2012-2016) 的分析.
- 包括34,727名正常血压的成年人 (18-69岁) 在2017年进行了症状查.
- 使用了考克斯模型,调整了诸如BMI,基线血压,睡眠时间和抑郁症状等混因素.
主要成果:
- 报告了习惯性打 (23.6%),早晨疲劳 (16.6%) 和过度白天嗜睡 (19.1%) 的发生率.
- 在中位数3.1年的随访期间,治疗高血压的发生率为3.8%.
- 习惯性打 (aHR 1.17) 和过度白天嗜睡 (aHR 1.42) 显著增加了高血压风险,显示了与症状频率的剂量依赖关系.
结论:
- 自我报告的打和过度的白天嗜睡与更高的高血压风险有关.
- 这些症状可以作为有价值的公共卫生查工具,用于在初级保健机构预防高血压.
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