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Updated: Jun 14, 2025

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重新评估PIN1作为瘤学中使用中性抑制剂和PROTACs的治疗点

Chuan Liu1, Zhonghui Chen2, Tao Chen1

  • 1HitGen Inc., Shuangliu District, Chengdu, Sichuan 610200, P. R. China.

Journal of medicinal chemistry
|September 4, 2024
PubMed
概括

研究人员研究了Peptidyl-prolyl cis-trans异构酶NIMA相互作用1 (PIN1) 作为癌症标. 新型抑制剂和PROTACs被开发出来,但显示出有限的疗效,质疑PIN1.

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