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Updated: May 4, 2026

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
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化酸水凝导致在皮下注射后在体内停留时间更长

Aurélie Honfroy1,2,3,4, Jolien Bertouille1, Ana-Maria Turea1

  • 1Research Group of Organic Chemistry (ORGC), Vrije Universiteit Brussel, Pleinlaan 2, Brussels B-1050, Belgium.

Biomacromolecules
|September 4, 2024
PubMed
概括

化酸水凝在生物医学应用中表现出增强的刚性和稳定性. 具体类型显示在体内长时间存在,这表明了先进药物递送系统的潜力.

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Bioavailability Enhancement: Drug Stability Enhancement and GI Retention

Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...
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