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紧急手术影响了小肠神经内分泌瘤的瘤结果

Frederike Butz¹, Leonie Supper², Lisa Reinhard²

¹Department of Surgery, Campus Charité Mitte | Campus Virchow-Klinikum, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.

Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society

|September 4, 2024

概括

小肠神经内分泌瘤 (siNETs) 的紧急手术与较差的生存结果有关. 预防出现疾病的积极管理对于患有晚期siNET疾病的患者至关重要.

科学领域:

胃肠病学胃肠病学
手术瘤学手术瘤学
在瘤学瘤学.

背景情况:

小肠神经内分泌瘤 (siNETs) 经常因为肠道缺血或阻塞而出现紧急情况.
紧急手术对siNET预后的影响尚未得到充分证实.

研究的目的:

调查急诊与选择性手术之间的关联以及siNET患者的瘤结果.

主要方法:

从165名接受肠切除的siNET患者的临床病理学数据的回顾性分析.
紧急 (n=37) 和选择性 (n=128) 手术组之间的结果比较.

主要成果:

紧急手术与较少的手术前诊断 (48.6% vs 85.2%) 和完全瘤切除 (32.4% vs 50.8%) 相关.
紧急手术患者的5年总生存率 (85.2% vs 89.5%) 和无进展生存率 (26.7% vs 52.5%) 显著降低.
多变量分析证实紧急手术是整体存活时间的负预测因素.

结论:

在siNET患者的紧急手术与不良的瘤结果相关,包括较短的整体和无进展生存期.
强调预防紧急情况是改善晚期siNET疾病的结果至关重要的.

关键词:

小肠神经内分泌瘤小肠神经内分泌瘤紧急手术是紧急手术.瘤结局的结果.

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