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相关概念视频

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

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Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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Phylogenetic Trees03:21

Phylogenetic Trees

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Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.
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Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

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The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
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Formation of Species01:31

Formation of Species

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Speciation describes the formation of one or more new species from one or sometimes multiple original species. The resulting species are discrete from the parent species, and barriers to reproduction will typically exist. There are two primary mechanisms, speciation with and without geographic isolation—allopatric and sympatric speciation, respectively.
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Phylogeny01:23

Phylogeny

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Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
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Polytene Chromosomes02:04

Polytene Chromosomes

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Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also...
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相关实验视频

Updated: Jun 14, 2025

A High-Throughput In Situ Method for Estimation of Hepatocyte Nuclear Ploidy in Mice
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多种植物:快速的多种类型的多种类型的基因构成估计.

Zhi Yan1, Zhen Cao1, Luay Nakhleh1,2

  • 1Department of Computer Science, Rice University, Houston, TX 77005, United States.

Bioinformatics (Oxford, England)
|September 4, 2024
PubMed
概括
此摘要是机器生成的。

我们开发了Polyphest,这是一种新的计算方法,可以准确地估计多类的基系,即使有不完整的血统分类 (ILS). "多体"比现有方法快得多,并准确地重建了多体物种的进化历史.

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相关实验视频

Last Updated: Jun 14, 2025

A High-Throughput In Situ Method for Estimation of Hepatocyte Nuclear Ploidy in Mice
08:44

A High-Throughput In Situ Method for Estimation of Hepatocyte Nuclear Ploidy in Mice

Published on: April 19, 2020

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Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
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Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

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科学领域:

  • 进化生物学 进化生物学
  • 计算生物学 计算生物学
  • 基因组学就是基因组学.

背景情况:

  • 多体性在植物中很常见,但重建多体系谱在计算上具有挑战性.
  • 现有的方法往往忽略不完整的血统分类 (ILS) 或太慢.
  • 需要高效和强大的方法来估计多类的原始物种.

研究的目的:

  • 介绍Polyphest,一种新的计算方法,用于在多化和ILS存在时推断物种类型.
  • 评估Polyphest的表现与现有的多种类型的基因组估计方法相比.
  • 将Polyphest应用于经验数据以确认发现.

主要方法:

  • 多种植物从基因树中生成一个多层树,然后将其转换为物种类型.
  • 绕过计算密集的网络空间搜索.
  • 与PADRE (没有ILS) 和MPAllopp (有ILS) 进行比较.

主要成果:

  • 聚合物实现了与MPAllopp相似的准确性,同时速度明显更快.
  • 在精度方面,Polyphest的表现优于PADRE.
  • 应用于面包小麦,Polyphest证实了其全聚类起源,并确定了其最近的亲属.

结论:

  • 多体为多体生殖基重建提供了一种高效准确的解决方案.
  • 这种方法有效地处理了多化和不完整的血统分类.
  • 多胞体是研究多胞体生物的进化的一个有价值的工具.