超声波探针压力影响大动脉壁硬度:一个患者特定的计算研究腹腔大动脉动脉瘤
Marta Irene Bracco1, Ali Akbar Karkhaneh Yousefi2, Laurence Rouet3
1INSERM, Sainbiose, Mines Saint-Étienne, Saint-Étienne, France. martairene.bracco@gmail.com.
Annals of biomedical engineering
|September 4, 2024
概括
探头压力显著影响腹腔大动脉瘤 (AAA) 壁硬度测量. 非线性壁的行为对于理解这种效应至关重要,为AAA管理中的超声波成像提供了新的临床见解.
科学领域:
- 生物医学工程 生物医学工程
- 医疗成像医学成像
- 计算力学 计算力学 计算力学
背景情况:
- 超声波 (US) 影像对于管理腹腔大动脉动脉瘤 (AAA) 是至关重要的.
- 在AAA中的周期直径变化,可以通过US测量,随着探头施加的压力而增加.
- 了解这种由压力引起的变化对于准确的AAA评估至关重要.
研究的目的:
- 为了彻底调查探头压力对AAA墙壁度的影响.
- 量化不同的探头压力如何影响AAA机械性能.
- 探索大动脉壁和周围组织的特性在这种现象中的作用.
主要方法:
- 在患者特定的AAA几何形状中对脉动性血流和探针压力的有限元建模.
- 模拟非线性超弹性和线性弹性大动脉壁模型.
- 评估不同的周围组织硬度和探针压力水平 (轻,中等,坚固).
主要成果:
- 坚定的探针压力降低了测量的大动脉硬度,特别影响非线性壁模型.
- 大动脉壁材料刚度仅在非线性模型中发生变化,这表明应力-应变曲线的偏移.
- 周围组织硬度增加和动脉瘤延长降低了对探针压力的反应能力.
结论:
- 探头压力显著影响测量的AAA壁度.
- AAA壁的非线性行为对于确定应对探头压力的反应至关重要.
- 这一发现对改善AAA超声波诊断具有潜在的临床应用.
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