患有神经发育障碍的人群中体重指数的趋势
Miguel Garcia-Argibay1,2,3, Sebastian Lundström4,5, Samuele Cortese3,6,7,8,9
1School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
JAMA network open
|September 4, 2024
概括
与没有NDD的同龄人相比,患有神经发育障碍 (NDD) 的儿童在16年内BMI的增加更大. 这凸显了超重风险的增加以及对这一群体有针对性的预防肥胖的需要.
科学领域:
- 儿科健康 儿科健康
- 神经发育障碍 神经发育障碍
- 肥胖问题研究研究
背景情况:
- 神经发育障碍 (NDD),包括自闭症谱系障碍 (ASD) 和注意力缺陷/多动症障碍 (ADHD),越来越普遍.
- 患有NDD的个体面临肥胖的风险增加,但这个群体的长期体重指数 (BMI) 趋势仍未得到充分研究.
研究的目的:
- 在患有和没有NDD的儿童中调查2004年至2020年BMI的世俗变化.
- 为了比较各种NDD亚型儿童及其神经类型同龄人之间的BMI百分点趋势.
主要方法:
- 一项重复的横截面研究,利用瑞典儿童和青少年双胞胎研究的数据.
- 在1992年至2010年间出生于9岁至12岁的儿童中对NDD症状进行查,数据收集时间跨越2004年7月至2020年4月.
- 量子回归被用来建模BMI百分位数和分析长期趋势,比较具有和没有NDD的群体.
主要成果:
- 该研究包括24,969名双胞胎;4%的查结果为NDDs呈阳性.
- 从2004年到2020年,与没有NDD的年轻人相比,BMI在第85百分位数的显著增加被观察到.
- 这种分歧在患有自闭症和学习障碍的儿童中最为明显,在最新的队列中发现了更高的BMI百分位数.
结论:
- 与没有NDD的同龄人相比,患有NDD的儿童在16年期间的BMI显著增加.
- 这表明,随着时间的推移,患有NDD的儿童的超重和肥胖风险越来越高.
- 这些发现强调了针对这一弱势群体制定有针对性的肥胖预防策略的迫切需要.
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