在头痛障碍和偏头痛中暴露于开放燃烧坑
Jason J Sico1,2,3,4, Sarah E Anthony1,2, Manali Phadke1,5
1Research, Education, Evaluation and Engagement Activities Center for Headache, Headache Centers of Excellence, US Department of Veterans Affairs (VA), Orange, Connecticut.
JAMA network open
|September 4, 2024
概括
暴露于开放的燃烧坑与退伍军人中新发头痛和偏头痛疾病的发病率较高有关. 这项研究强调了剂量依赖的关联,强调了医疗保健机构查的必要性.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 军事医学 军事医学
背景情况:
- 美国军方广泛使用开放式焚烧坑来处理废物.
- 缺乏对开放式燃烧坑作为头痛疾病风险因素的系统调查.
研究的目的:
- 评估暴露于开放燃烧坑和头痛和偏头痛疾病的发生率之间的关联.
主要方法:
- 使用退伍军人卫生管理局头痛队列,国防部和空中危险和开放烧坑登记处的数据进行回顾性队列研究.
- 从2014年4月到2022年10月,247,583名退伍军人的电子健康记录与链接注册表数据.
- 评估了暴露变量,包括与开放燃烧坑相关的接近,持续时间和职责,不包括先前存在头痛的参与者.
主要成果:
- 在开放燃烧坑附近有相关职责的退伍军人显示,医疗诊断的头痛障碍 (AOR,1.59) 和偏头痛 (AOR,1.60) 的几率明显更高.
- 观察到剂量依赖的关系;较高的累积暴露 (290-448天和>448天) 与头痛和偏头痛的几率增加相关.
- 暴露的最高四分位数 (>448天) 的AOR为1.55的头痛和1.48的偏头痛.
结论:
- 在露天燃烧坑暴露和新出现的医学诊断的头痛和偏头痛之间存在剂量依赖的关联.
- 调查结果表明,露天燃烧坑暴露是军事人员头痛障碍的重要危险因素.
- 建议将这些疾病的查纳入医疗保健机构,为潜在暴露的退伍军人提供服务.
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