癌症患者的相似度指标的识别:范围审查协议
Iryna Manuilova1,2, Jan Bossenz1, Annemarie Bianka Weise1
1Junior Research Group (Bio-) Medical Data Science, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
JMIR research protocols
|September 4, 2024
概括
本综述绘制了患者相似性如何定义和用于癌症研究,以推进个性化医疗. 了解这些相似之处有助于开发有针对性的治疗方法,并改善瘤学患者的治疗结果.
科学领域:
- 瘤学和生物信息学
- 个性化医学和精确瘤学
背景情况:
- 了解患者的相似性对于个性化癌症医学至关重要.
- 它有助于识别生物标志物,治疗策略,并改善患者的治疗结果.
- 识别相似的患者支持瘤学家在临床决策中.
研究的目的:
- 系统地总结和绘制癌症研究中患者相似性的现有证据.
- 了解患者相似性如何定义和在临床实践中使用.
- 为未来的个性化癌症护理研究提供基础.
主要方法:
- 在多个数据库 (例如,科学网,PubMed) 进行了全面的文献搜索.
- 研究选择涉及标题/摘要选,分歧解决和使用Rayyan的全文选.
- 该审查遵循PRISMA-ScR指南,该协议在JMIR中注册.
主要成果:
- 最初的搜索结果显示,从1998年到2024年2月期间,有1183个独一无二的记录.
- 该审查目前处于2024年3月的全文评估阶段.
- 数据提取将使用预先测试的图表模板进行.
结论:
- 这个范围审查协议系统地绘制了癌症患者相似性的证据.
- 它定义了在该领域使用的数据源,方法和方法.
- 结果将为未来的研究和个性化癌症护理的临床应用提供信息.
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