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Updated: Jun 14, 2025

Isolation of Group 2 Innate Lymphoid Cells from Mouse Nasal Mucosa to Detect the Expression of CD226
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Published on: May 10, 2022

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多发性硬化症相关遗传变异CD226Gly307Ser对人类CD8T细胞功能的影响

Elena Morandi1, Véronique Adoue1, Isabelle Bernard1

  • 1From the Infinity-Toulouse Institute for Infectious and Inflammatory Diseases (E.M., V.A., I.B., Y.A., F.M., A.S.D., A.A., A.S.), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR 1291, Centre National de la Recherche Scientifique (CNRS) UMR 5051, Université Paul Sabatier (UPS), Toulouse, France; Institute of Experimental Immunology (E.F., N.N., B.B.), University of Zurich, Switzerland; and Cancer Research Center of Toulouse (CRCT) (L.M.), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR 1037, Centre National de la Recherche Scientifique (CNRS), Université Paul Sabatier (UPS), Toulouse, France.

Neurology(R) neuroimmunology & neuroinflammation
|September 4, 2024
PubMed
概括

CD226风险变体 (rs763361) 通过增强IFNγ信号通路,影响CD8T细胞功能. 这一发现有助于了解其在多发性硬化症等免疫媒介疾病中的作用.

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