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Updated: Jun 14, 2025

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内皮GATA3在内毒素败血症期间参与凝固纤维素过敏的恒常性

Moyuru Hayashi1, Shin'ya Ohmori2, Yoshiko Kawai1

  • 1Division of Physiology, Tohoku Medical and Pharmaceutical University, School of Medicine, 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi 983-8536, Japan.

Experimental animals
|September 4, 2024
PubMed
概括

转录因子GATA3通过调节等离子体激活因子抑制剂-1 (PAI-1) 和组织等离子体激活因子 (tPA) 水平,保护免受败血症诱导的肺损伤和肺栓塞. 缺乏GATA3会增加对内毒素诱导的肺栓塞的易感性.

关键词:
格拉特 (Gata) 是一个血栓塞栓症 血栓塞栓症 是一种纤维化解是一种纤维化解.这是一种血症.

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