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移植患者的孕产妇和新生儿结局:单中心观察性研究
Ayse Serra Artan1, Safak Mirioglu2, Elif Ünal3
1Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Istanbul University, Istanbul, Turkey. ayseserra@gmail.com.
Wiener klinische Wochenschrift
|September 4, 2024
概括
移植受体 (KTRs) 怀孕导致子宫前和早产率较高,新生儿后果相似. 重要的是,KTR移植功能在分娩后显著下降.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植 移植 移植 移植
- 产科 产科 产科 产科 产科
背景情况:
- 在移植接受者 (KTRs) 中,怀孕对母亲和新生儿的健康有风险.
- 与一般人群相比,KTRs怀孕后的长期异位移植功能数据有限.
研究的目的:
- 为了比较经历怀孕的KTR与匹配的非移植对照组的孕产妇和新生儿结局.
- 为了评估怀孕后KTRs的长期移植功能.
主要方法:
- 追溯性,单中心研究比较孕妇KTR与年龄相匹配的对照.
- 孕产妇的结果:妊娠前,出血,住院,和复合结局 (移植失败,血清肌素的翻倍).
- 新生儿结局:妊娠年龄,早产,死亡率,NICU入院,Apgar分数,出生体重.
主要成果:
- 在KTR怀孕中,孕产前和早产率显著增加.
- KTR怀孕导致出生体重降低和更长的孕产妇住院时间.
- 移植功能在分娩后下降,其中11.3%的KTR经历了不良的结局.
结论:
- KTRs增加了孕前和早产的风险,但可比的新生儿死亡率和NICU入院率.
- 移植接受者的移植功能在分娩后显著恶化.
- 这些发现凸显了怀孕期间和之后需要密切监测KTR的必要性.
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