在基于诊断超声波平台的超声波血栓溶解期间进行2D空间时空被动腔位成像和评估
Qi Zhang1, Yifei Zhu1, Guofeng Zhang1
1Key Laboratory of Modern Acoustics (MOE), Department of Physics, Collaborative Innovation Center of Advanced Microstructure, Nanjing University, Nanjing 210093, China.
Ultrasonics sonochemistry
|September 4, 2024
概括
这项研究引入了一种先进的被动化成像系统,用于实时监测超声波治疗. 这种新方法可以精确的2D定量评估声腔,提高处理的安全性和效率.
科学领域:
- 生物医学超声波 生物医学超声波
- 声学化声学化声学化
- 医疗成像医学成像
背景情况:
- 在生物医学应用中,声波化是至关重要的,但不受控制的化可能会损害组织.
- 洞穴动态的实时监测和定量评估对于优化超声波治疗至关重要.
- 现有的洞穴检测方法在实时临床应用方面存在局限性.
研究的目的:
- 开发和验证一个自适应的时间划分多重复合被动化成像 (PCI) 系统集成到诊断超声波平台.
- 为了实现同时实时洞穴监测和B模式成像,用于二维定量评估.
- 为了提高PCI性能,使用一个优化的延迟和总和 (DAS) 算法,以最小的差异 (MV) 束former.
主要方法:
- 集成一个自适应的时间划分多重复合被动化成像 (PCI) 系统与商业诊断超声波平台.
- 实施了一种改进的延迟和总和 (DAS) 算法,具有最小方差 (MV) 束变量器,以提高分辨率和减少侧叶效应.
- 使用盐水,纳米钻石 (ND) 和冷纳米钻石 (N-AND) 溶液在超声波血栓溶解过程中进行二维腔位评估系统的应用.
主要成果:
- 开发的系统允许同时可视化治疗进展,并对化剂量进行二维定量评估.
- 改进的DAS算法与MV光束制造器增强了轴分辨率,并最大限度地减少了PCI中的侧叶效应.
- 该系统在不同声压和微泡度下成功评估了化活动,包括在超声血栓溶解过程中.
结论:
- 增强的二维化监测和评估系统为评估化介导的效应提供了宝贵的工具,如超声波血栓溶解.
- 这项技术弥合了实验室研究和实践临床需求之间的差距,用于实时的时空洞穴评估.
- 该系统提供了洞察洞穴机制的洞察力,并有助于优化基于洞穴的治疗应用.
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